Author's Organization：Faculty of Pharmaceutical Sciences, Nagoya City University Faculty of Pharmaceutical Sciences, Nagoya City University Faculty of Pharmaceutical Sciences, Nagoya City University Faculty of Pharmaceutical Sciences, University of Tokyo
The 3, 6-diacetate (3) of grayanotoxin-II (1), a diterpene isolated from Leucothoe grayana, was treated with lead tetraacetate to afford 1, 3, 6-triacetyl-1 (R), 6 (R)-grayanol (4.) The structure of 4 was established by spectroscopic means and X-ray analysis of the ethylidene derivative (5). Alkaline hydrolysis of 4 gave a ketal (7).
