Abstract
The reaction of diketene with cyanamide gave 2-amino-6-methyl-4H-1, 3-oxazin-4-one, which was transformed to 6-methyluracil by refluxing it in acetic acid. Diketene also reacted with monosubstituted cyanamides to give 1, 3-oxazin-4-one derivatives, which could be similarly converted into 1-substituted 6-methyluracils. The reaction of diketene with dicyanodiamide afforded 2-guanidino-6-methyl-4H-1, 3-oxazin-4-one, which, on treatment with ammonia, afforded 2-guanidino-4-hydroxy-6-methylpyrimidine.
