Studies on Monoterpene Glucosides and Related Natural Products. XLI. Chemical Conversion of Geniposide into 10-Hydroxyloganin

Abstract

Geniposide (9) was chemically converted into 10-hydroxyloganin (3a), which is presumed to be a precursor for secologanin (2). The stereoisomers 8a, 18a and 19a were also prepared. The absolute configurations of these four compounds were determined on the basis of chemical reactions and NMR measurements.