Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Metabolic Products of Aspergillus terreus. V. Demethylation of Asterriquinones
KUNIZO ARAISAKAE SHIMIZUYASUHISA TAGUCHIYUZURU YAMAMOTO
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Keywords: dimethylallyl
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1981 Volume 29 Issue 4 Pages 991-999

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Abstract

Demethylation of asterriquinones (AQ, bisindolyl-dimethoxyl benzoquinones) was investigated in connection with the determination of their structures and studies of their antitumor activity. Usually, the demethylation proceeded smoothly with KOH, but several types of side reactions were observed with acidic reagents.

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© The Pharmaceutical Society of Japan
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