New Methods and Reagents in Organic Synthesis. 14. A Simple Efficient Preparation of Methyl Esters with Trimethylsilyldiazomethane (TMSCHN2) and Its Application to Gas Chromatographic Analysis of Fatty Acids

NORIO HASHIMOTO; TOYOHIKO AOYAMA; TAKAYUKI SHIOIRI

doi:10.1248/cpb.29.1475

New Methods and Reagents in Organic Synthesis. 14. A Simple Efficient Preparation of Methyl Esters with Trimethylsilyldiazomethane (TMSCHN₂) and Its Application to Gas Chromatographic Analysis of Fatty Acids

橋本典夫, 青山豊彦, 塩入孝之

著者情報

キーワード: gas chromatographic analysis

ジャーナルフリー

1981 年 29 巻 5 号 p. 1475-1478

DOI https://doi.org/10.1248/cpb.29.1475

詳細

抄録

Trimethylsilyldiazomethane (TMSCHN₂), known as a stable and safe substitute for highly toxic and explosive diazomethane in the Arndt-Eistert synthesis and homologation of carbonyl compounds, has smoothly reacted with various carboxylic acids in methanolic benzene solution to give the corresponding methyl esters in excellent yields.

責任著者(Corresponding author)

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