Author's Organization：Pharmaceutical Institute, Tohoku University Pharmaceutical Institute, Tohoku University Pharmaceutical Institute, Tohoku University Pharmaceutical Institute, Tohoku University
Irradiation of a solution of acetone and diketene in 2-propanol gave 4-(2-hydroxy-2-methylpropyl) oxetan-2-one (1) in 63% yield. 4-(2-Hydroxy-2-methylbutyl)- and 4-(2-hydroxy-2-ethylbutyl) oxetan-2-one (2 and 3) were similarly prepared. Treatment of compound 1 with hydrogen chloride in alcohol gave ethyl (E)-5-methyl-2, 4-hexadienoate (4). Ring transformation of the oxetanones (1 and 2) into pyranone derivatives was also investigated.
