The Constituents of Schizandra chinensis BAILL. X. The Structures of γ-Schizandrin and Four New Lignans, (-)-Gomisins L₁ and L₂, (±)-Gomisin M₁ and (+)-Gomisin M₂

Abstract

Four new dibenzocyclooctadiene lignans, named (-)-gomisins L₁ (6) and L₃ (7), (±)-gomisin M₁ (8) and (+)-gomisin M₂ (9), were isolated from the fruits of Schizandra chinensis BAILL. (Schizandraceae). Their absolute structures were elucidated by means of chemical and spectral studies. The stereostructure of γ-schizandrin (1, dl-form), the plane structure of which had already been suggested by Kochetkov et al. and Liu et al., was also elucidated on the basis of chemical and spectral studies.