Studies on the Constituents of Momordica charantia L. III. Characterization of New Cucurbitacin Glycosides of the Immature Fruits. Structures of Momordicosides G, F₁, F₂ and I

Abstract

Several non-bitter cucurbitacin glycosides were isolated together with two bitter cucurbitacin glycosides from the immature fruits of Momordica charantia L. (Cucurbitaceae), and four of the non-bitter glycosides, momordicosides G, F₁, F₂ and I, were characterized from chemical and spectral evidence as folows ; G, 3-O-β-D-allopyranoside of 5, 19-epoxy-25-methoxy-5β-cucurbita-6, 23-dien-3β-ol ; F₁, 3-O-β-D-glucopyranoside of 5, 19-epoxy-25β-methoxy-5β-cucurbita-6, 23-dien-3β-ol ; F₂, 3-O-β-D-allopyranoside of 5, 19-epoxy-5β-cucurbita-6, 23-diene-3β, 25-diol ; I, 3-O-β-D-glucopyranoside of 5, 19-epoxy-5β-cucurbita-6, 23-diene-3β, 25-diol.