Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Isolation and Characterization of Cardiac Steroids from Seeds of Elaeopendron glaucum PERS. Structures of Elaeodendrosides A, D, E, H, I, J and Elaeodendrogenin
島田 和武興野 智子南原 利夫内田 逸郎
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キーワード: cardiac activity
ジャーナル フリー

1982 年 30 巻 11 号 p. 4075-4081

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抄録
Six cardiac glycosides having a methylenedioxy group in the sugar moiety, elaeodendroside A, D, E, H, I and J, were isolated from seeds of Elaeodendron glaucum PERS. Their structures were elucidated on the basis of chemical correlation with elaeodendroside A, which was characterized by X-ray analysis. A new cradiac steroid named elaeodendrogenin was also isolated from the same plant materials and its structure was established by direct comparison with a synthetic sample obtained from digitoxigenin. The cardiac activities of these compounds were tested with Straub's preparation.
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© The Pharmaceutical Society of Japan
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