Saponins of Zu-Tziseng, Rhizomes of Panax japonicus C.A. MEYER var. major (BURK.) C.Y. Wu et K.M. FENG, collected in Yunnan, China

Abstract

From rhizomes of Panax japonicus var. major (Chinese name : Zu-Tziseng) collected in Yunnan, China, two known oleanolic acid-saponins, chikusetsusaponin-IVa (6) and-V (1), two dammarane-saponins, ginsenoside-Rd (3) and notoginsenoside-R2 (2), and two new dammarane-saponins named majonoside-R1 (7) and-R2 (13) were isolated. By means of ¹³C-nuclear magnetic resonance (NMR) and mass spectrometry, the common aglycone of both new saponins was proved to be 3β, 6α, 12β, 25-tetrahydroxy-(20S, 24S)-epoxy-dammarane (11) (ocotillol-type triterpene) and the structures of 13 and 7 were elucidated to be 6-O-β-xylopyranosyl (1→2)-β-glucopyranoside and 6-O-β-sophoroside of 11, respectively.