Abstract
Compounds (I and II) which inhibited lipid peroxides formation (in in vitro experiments) were isolated together with various flavonoids from the roots of Scutellaria baicalensis GEORGI. From the analytical and physical data, compounds I and II were identified as (2S)-2', 5, 6', 7-tetrahydroxy-flavanone and (2R, 3R)-2', 3, 5, 6', 7-pentahydroxy-flavanone, respectively. Compound II inhibited the lipid peroxide formation by Fe2+ and ascorbic acid. Compounds I and II inhibited the lipid peroxide formation induced by adenosine diphosphate and reduced nicotinamide adenine dinucleotide phosphate in rat liver homogenate.
