Studies on Fluorinated Pyrimidines. III. Synthesis of 1-Acyl- and 1, 3-Diacyl-5-alkoxycarbonyl-5-fluoro-6-substituted-5, 6-dihydrouracils

OSAMU MIYASHITA; KOICHI MATSUMURA; HIROSHI SHIMADZU; NAOTO HASHIMOTO

doi:10.1248/cpb.30.1860

OSAMU MIYASHITA, KOICHI MATSUMURA, HIROSHI SHIMADZU, NAOTO HASHIMOTO

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Keywords: isocyanates

JOURNAL FREE ACCESS

1982 Volume 30 Issue 5 Pages 1860-1864

DOI https://doi.org/10.1248/cpb.30.1860

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Abstract

1-Acyl- and 1, 3-diacyl-5-alkoxycarbonyl-5-fluoro-6-substituted-5, 6-dihydrouracils were synthesized for study as a class of pro-drugs of 5-fluorouracil (5-FU).

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