A heptadecapeptide amide, H-Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2, corresponding to the entire amino acid sequence of human gastric I, was synthesized by the solution method. This peptide inhibited lactate dehydrogenase activity by 87.6% at a concentration of 300 pg/ml. This peptide was tested for suppression of PHA-induced lymphocyte proliferation, but showed no significant activity.
