著者所属：Pharmaceutical Institute, Tohoku University Pharmaceutical Institute, Tohoku University Pharmaceutical Institute, Tohoku University Pharmaceutical Institute, Tohoku University
The first enantioselective synthesis of (-)-physostigmine (1), a potent cholinesterase-inhibiting alkaloid from Physostigma venenosum Balf., has been accomplished using (S)-(-)-benzyl 2, 3-epoxypropyl ether (5) as a chiral synthon.
