Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
NEW METHODS AND REAGENTS IN ORGANIC SYNTHESIS. 31. LITHIUM TRIMETHYLSILYLDIAZOMETHANE : A NEW SYNTHON FOR THE PREPARATION OF TETRAZOLES
Toyohiko Aoyama, Takayuki Shioiri
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Keywords: tetrazole
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1982 Volume 30 Issue 9 Pages 3450-3452

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Abstract
Lithium trimethylsilyldiazomethane, prepared from trimethylsilyldiazomethane and lithium diisopropylamide, reacts smoothly with methyl esters of carboxylic acids to give 2-substituted 5-trimethylsilyltetrazoles in good yields.
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© The Pharmaceutical Society of Japan
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