Syntheses of Heteroaromatic Carboxylic Acids Closely Related to Fusaric Acid

HIROSHI YAMANAKA; MICHINAO MIZUGAKI; TAKAO SAKAMOTO; MATAICHI SAGI; YOSHIO NAKAGAWA; HIDEKI TAKAYAMA; MASATAKA ISHIBASHI; HIROSHI MIYAZAKI

doi:10.1248/cpb.31.4549

HIROSHI YAMANAKA, MICHINAO MIZUGAKI, TAKAO SAKAMOTO, MATAICHI SAGI, YOSHIO NAKAGAWA, HIDEKI TAKAYAMA, MASATAKA ISHIBASHI, HIROSHI MIYAZAKI

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Keywords: isoxazole

JOURNAL FREE ACCESS

1983 Volume 31 Issue 12 Pages 4549-4553

DOI https://doi.org/10.1248/cpb.31.4549

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Abstract

In order to investigate the generality of a chain-elongation reaction observed in the metabolism of fusaric acid (5-butyl-2-pyridinecarboxylic acid) and its derivatives, various heteroaromatic (diazine, 1, 3-azole, and 1, 2-azole) carboxylic acids with a normal alkyl side-chain were synthesized.

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