Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
The Structures of 15-Dehydro-prostaglandin B1 Dimers
NOBUYUKI HAMANAKA, MASAAKI TODA, SHIGERU TAKAOKA, MASAKI HAYASHI, TAKASHI IWASHITA
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Keywords: prostaglandin B1 dimer
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1983 Volume 31 Issue 2 Pages 557-559

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Abstract
Prostaglandin Bx (PGBx), a complex mixture of closely related oligomers of Prostaglandin B1 (PGB1) or 15-dehydro-PGB1 which has unique biological activities, is formed under basic conditions. For mechanistic studies of the oligomerization, two dimers of 15-dehydro-PGB1 were prepared under mild conditions and their structures were determined by means of nuclear magnetic resonance (NMR) spectroscopic studies.
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© The Pharmaceutical Society of Japan
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