Saponin and Sapogenol. XXXVI. Chemical Constituents of Astragali Radix, the Root of Astragalus membranaceus BUNGE. (3). Astragalosides III, V, and VI

Abstract

Based on chemical and physicochemical investigations including carbon-13 nuclear magnetic resonance (¹³C-NMR) examinations and methylation analyses, the structures of three astragalosides, which were isolated from Astragali Radix, the root of Korean Astragalus membranaceus BUNGE (Leguminosae), were elucidated : astragaloside III is 3-O-[β-D-glucopyranosyl (1→2)-β-D-xylopyranosyl] cycloastragenol (3), astragaloside V is 3-O-[β-D-glucopyranosyl (1→2)-β-D-xylopyranosyl]-25-O-β-D-glucopyranosyl-cycloastragenol (5) and astragaloside VI is 3-O-[β-D-glucopyranosyl (1→2)-β-D-xylopyranosyl]-6-O-β-D-glucopyranosyl-cycloastragenol (6).