Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
EVIDENCE FOR THE PHYSIOLOGICAL FUNCTION OF ALKALINE PHOSPHATASE
飯泉 祐一平野 和行杉浦 衛飯野 四郎鈴木 宏織田 敏次
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キーワード: phosphate transporter
ジャーナル フリー

1983 年 31 巻 2 号 p. 772-775

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抄録
The evidence for a possible role of intestinal alkaline phosphatase in the physiologic state is offered in this paper. A phosphate transport system operating at a physiological pH is found in the upper part of the small intestine where the alkaline phosphatase is maximally concentrated. The phosphate transport was affected by various inhibitors and antiserum to rat intestinal alkaline phosphatase. In conclusion, alkaline phosphatase may function not only as a hydrolytic enzyme of phosphoester but also as a phosphate transporter in the physiologic state.
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© The Pharmaceutical Society of Japan
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