Abstract
Autoxidation of cholanic acid in an aqueous acetone solution containing 0.2M acetate buffer (pH 5.0) and ferrous sulfate gave three C (12)-keto products, A, B, and C. The main product A was elucidated to be 12-oxo-5β-cholan-24-oic acid. The minor product B was probably 12, 23-dioxo-5β-cholan-24-oic acid. The other carbonyl function of the diketo minor product C was assumed to be situated in ring A or B at a position strongly affected by the angular C (19)-methyl group.
