Abstract
The synthesis of 6, 7-dihydro-5H-pyrimidino[5, 4-c]carbazoles (3) was achieved by cyclisation of 1, 2, 3, 4-tetrahydrocarbazol-4-ones with triformamidomethane. The oxydation with potassium permanganate of 6, 7-dihydro-5H-pyrimidino[5, 4-c]carbazoles gave the 7H-pyrimidino[5, 4-c]carbazoles (4). The reactions of the pyrimidinocarbazoles (4a) and (4e) with lithium organic compounds afforded 4-substituted derivatives (6). The structure of the derivatives was determined by 1H-NMR and Overhauser effect.
