Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Preparation and Spectral Properties of 2-(2, 4-Dichlorophenyl)-2-(1, 2, 3, 5-tetrazol-1-ylmethyl)-1, 3-dioxolan-4-ylmethanol and Its Benzoate and Methanesulfonate
濱田 喜樹竹内 烈山本 和子広田 穣末沢 裕子
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キーワード: alkylation
ジャーナル フリー

1984 年 32 巻 1 号 p. 302-304

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抄録
The title compounds were prepared by nucleophilic substitution by tetrazole anion of the corresponding bromide (1). followed by hydrolysis and methanesulfonylation. The site of alkylation of the tetrazole anion was determined by comparison of the 13C-nuclear magnetic resonance spectrum with those of N-methyltetrazoles.
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© The Pharmaceutical Society of Japan
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