1985 Volume 33 Issue 10 Pages 4228-4234
Administration of 3H- or 13C-labeled acyclic monoterpenes to Gardenia jasminoides f. grandiflora cell suspension cultures showed that tarennoside (20) and gardenoside (21) were biosynthesized in the cell cultures via the cyclization of 10-oxogeranial (5a)/10-oxoneral (5b) to iridodial cation (14). followed by extensive randomization of the carbon atoms 3 and 11. Furthermore, the intermediacy of (R)-(+)-and (S)-(-)-10-hydroxycitronellol (24a, 24b) and (R)-(+)-and (S)-(-)-9, 10-dihydroxycitronellol (28a, 28b) was disproved.