Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Stereoselective Reactions. X. Total Synthesis of Optically Pure Antitumor Lignan, Burseran
KIYOSHI TOMIOKA, TSUNEO ISHIGURO, KENJI KOGA
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Keywords: deoxypodorhizon
JOURNAL FREE ACCESS

1985 Volume 33 Issue 10 Pages 4333-4337

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Abstract

Optically pure trans- and cis-burseran (4, 10) were stereoselectively synthesized in an unequivocal manner. Comparison of their behaviors on gas chromatography indicated that naturally occurring antitumor lignan, burseran, is the trans-isomer.

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© The Pharmaceutical Society of Japan
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