Carbapenem and Penem Antibiotics. II. Synthesis and Antibacterial Activity of 2-Functionalized-methyl Carbapenems Related to Asparenomycins
キーワード:
antibacterial activity
1985 年 33 巻 10 号 p. 4361-4370
詳細
1985 年 33 巻 10 号 p. 4361-4370
Racemic 2-acetoxymethyl and 2-(heteroaromatic) thiomethyl carbapenems having a 1-(hydroxymethyl) ethylidene or cyclic carbonate side-chain at C-6 (5, 25, 38, 40, 42, and 36b, 23b, 28b, 30b, 32b, 34b) were synthesized from the common intermediates 3a and 3b, and their antibacterial activities were determined.
