Carbapenem and Penem Antibiotics. IV. Synthesis and Antibacterial Activity of (5R*, 6S*)-6-[(R*)-1-Hydroxyethyl]-2-functionalized-methyl Carbapenem and Penem Derivatives

HISAO ONA; SHOICHIRO UYEO; TAKASHI FUKAO; MASAYOSHI DOI; TADASHI YOSHIDA

doi:10.1248/cpb.33.4382

Carbapenem and Penem Antibiotics. IV. Synthesis and Antibacterial Activity of (5R^*, 6S^*)-6-[(R^*)-1-Hydroxyethyl]-2-functionalized-methyl Carbapenem and Penem Derivatives

小名寿男, 上尾庄一郎, 深尾孝, 土肥正善, 吉田正

著者情報

キーワード: antibacterial activity

ジャーナルフリー

1985 年 33 巻 10 号 p. 4382-4394

DOI https://doi.org/10.1248/cpb.33.4382

詳細

抄録

Racemic 2-acetoxymethyl and 2-(heteroaromatic) thiomethyl carbapenem and penem antibiotics having a 1-(R^*)-hydroxyethyl side-chain at C-6 (6, 7, 8, and 45, 59, 47, 49, 51) were synthesized, and their antibacterial activities were determined.

責任著者(Corresponding author)

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