Synthesis of the Metabolites and Degradation Products of 2-Amino-7-isopropyl-5-oxo-5H-[1] benzopyrano [2, 3-b] pyridine-3-carboxylic Acid (Amoxanox)
キーワード:
degradation product
1985 年 33 巻 10 号 p. 4432-4437
詳細
1985 年 33 巻 10 号 p. 4432-4437
The metabolites and degradation products of 2-amino-7-isopropyl-5-oxo-5H-[1] benzopyrano-[2, 3-b] pyridine-3-carboxylic acid (Amoxanox, AA-673, 1), a promising drug for the treatment of bronchial asthma, were synthesized to confirm the proposed structures and to determine their activity in the rat passive cutaneous anaphylaxis test.
