Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Condensed Heteroaromatic Ring Systems. IV. Synthesis of Naphthyridine Derivatives by Cyclization of Aminopyridineacrylic Esters
坂本 尚夫根東 義則山中 宏
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キーワード: pyridineacrylic ester
ジャーナル フリー

1985 年 33 巻 11 号 p. 4764-4768

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The reaction of aminohalopyridines with ethyl acrylate in the presence of palladium (II) acetate and triarylphosphine gave ethyl aminopyridineacrylates. The cyclization of the resulting acrylates under basic conditions gave naphthyridinones having a carbostyril-type moiety.

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© The Pharmaceutical Society of Japan
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