Synthesis of 2-Arylsuccinates by Oxidative 1, 2-Aryl Migration of 3-Aroylpropionic Acids or 5-Arylfuran-2 (3H)-ones with Thallium (III) Nitrate

Abstract

Treatment of 3-aroylpropionic acids (1) with thallium (III) nitrate causes smooth 1, 2-aryl migration to give dimethyl 2-arylsuccinates (2) in good yields. Similar transformation of 5-arylfuran-2 (3H)-ones (3) with thallium (III) nitrate to 1-methyl 2-arylsuccinates (4) is also described.