Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
A TOTAL AND PRACTICAL SYNTHESIS OF ERGOT ALKALOID, (±)-AURANTIOCLAVINE
Fumio YamadaYoshihiko MakitaTomoko SuzukiMasanori Somei
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Keywords: nitro-olefin
JOURNAL FREE ACCESS

1985 Volume 33 Issue 5 Pages 2162-2163

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Abstract
The first synthesis of (±)-aurantioclavine by a convenient and practical five-step synthetic method, involving a new intra-molecular cyclization of nitro-olefin, is achieved starting from 3-formylindole with a 31% overall yield without using any protective groups.
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© The Pharmaceutical Society of Japan
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