Author's Organization:Faculty of Pharmaceutical Sciences, Kyushu University Faculty of Pharmaceutical Sciences, Kyushu University Faculty of Pharmaceutical Sciences, Kyushu University The Institute of Physical and Chemical Research (Rikagaku Kenkyusho) The Institute of Physical and Chemical Research (Rikagaku Kenkyusho) Faculty of Pharmaceutical Sciences, Kyushu University
(S)-13-Hydroxy-9Z, 11E-octadecadienoic acid, a defensive substance in rice, was synthesized with high enantioselectivity by the reduction of the corresponding ketone with yeasts.