Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Hypolipidemic Agents. II. 3-(4-Phenoxybenzoyl)-propionic Acid Derivatives
冨沢 一雪亀尾 一弥松永 融斉藤 秀次細田 和昭浅見 由美子曽田 馨
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キーワード: hypolipidemic activity
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1985 年 33 巻 6 号 p. 2386-2394

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抄録

3-(4-Phenoxybenzoyl) propionic acids were prepared and tested for hypolipidemic activity in normal rats. A structure-activity relationship study showed that the 2-acetylthio derivative had hypolipidemic activity. Among these compounds, 2-acetylthio-[3-(4-chlorophenoxy) benzoyl] propionic acid possessed very potent activity.

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© The Pharmaceutical Society of Japan
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