Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Isolation and Characterization of Cinobufagin 3-Glutaroyl-L-arginine Ester from Bufo bufo gargarizans CANTOR
島田 和武盧 戴燮大石 和夫南原 利夫
著者情報
キーワード: active ester method
ジャーナル フリー

1985 年 33 巻 7 号 p. 2767-2771

詳細
抄録
A new bufotoxin having glutaric acid as a dicarboxylic acid moiety was found in the Korean toad, Bufo bufo gargarizans CANTOR. This new bufotoxin was separated from the dried toad by usual chromatographic methods including reversed phase high-performance liquid chromatography, and its structure was elucidated to be cinobufagin 3-glutaroyl-L-arginine ester by degradative and synthetic means. In addition, seven known bufogenins and eight known bufotoxins were isolated and characterized.
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© The Pharmaceutical Society of Japan
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