STUDIES ON QUINOLIZINE DERIVATIVES XVIII. SYNTHESES OF AZABENZOCYCL [3. 3. 3] AZINE DERIVATIVES

Abstract

1, 4-Diazabenzo [j] cycl [3. 3. 3] azine derivative (IX) and 1-azabenzo-[h] cycl [3. 2. 2] azine derivative (VII) were synthesized by the reaction of dimethyl acetylenedicarboxylate (DMAD) with 3-cyano-4-imino-4H-isoquinolino [1, 2-a] pyrimidine (IV). Benzo [g] cycl [3. 2. 2] azine derivative (VIII) was synthesized using the reaction of DMAD (VI) with methyl 3-cyano-4-imino-4H-isoquinolino [1, 2-a] pyridine-1-carboxylate (V).