Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Useful Syntheses of β-Amino-γ-ketobutyric Acid Derivatives from Aspartic Acid
関 雅彦窪田 均守屋 多聞山岸 正文西本 茂松本 和男
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キーワード: Friedel-Crafts reaction
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1986 年 34 巻 11 号 p. 4516-4522

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C-Acylation of α-isocyanosuccinate having an aspartic acid skeleton, Dakin-West and Friedel-Crafts reactions with 2-oxazolin-5-oneacetate (aspartic acid azlactone) were found to be efficient methods for the preparation of various β-amino-γ-ketobutyric acid derivatives.

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© The Pharmaceutical Society of Japan
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