Author's Organization:Faculty of Engineering, Ehime University Faculty of Engineering, Ehime University Faculty of Engineering, Ehime University Research Center, Mitsui Toatsu Chemicals Research Center, Mitsui Toatsu Chemicals
Main metabolites of 1-hexylcarbamoyl-5-fluorouracil, i.e., 1-(5-carboxypentylcarbamoyl)-, 1-(3-carboxypropylcarbamoyl)-, 1-(5-hydroxyhexylcarbamoyl)- and 1-(5-oxohexylcarbamoyl)-5-fluorouracils, were synthesized on a large scale.