Author's Organization：Department of Chemistry, Tokyo Institute of Technology Department of Chemistry, Tokyo Institute of Technology Department of Chemistry, Tokyo Institute of Technology Department of Chemistry, Tokyo Institute of Technology
Catalytic hydrogenation of the (22R)-unsaturated loctone 8 and its (22S)-epimer 9 afforded stereoselectively the (22R, 24R)-saturated lactone 10 and the (22S, 24S)-isomer 11, respectively. The C-24 stereochemistry of the hydrogenated products was determined by their conversion into 24-ethylcholesterols.
