Lipid A and Related Compounds. XV. Efficient Synthesis of Novel Analogs of Glucosamine-4-phosphate, the Nonreducing Sugar Moiety of Lipid A

SHIN-ICHI NAKAMOTO; TOSHIO TAKAHASHI; KIYOSHI IKEDA; KAZUO ACHIWA

doi:10.1248/cpb.35.4517

SHIN-ICHI NAKAMOTO, TOSHIO TAKAHASHI, KIYOSHI IKEDA, KAZUO ACHIWA

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Keywords: lipid A analog, glucosamine derivative, 4-phosphorylated monosaccharide, antitumor activity, lethal toxicity, mitogenic activity

JOURNAL FREE ACCESS

1987 Volume 35 Issue 11 Pages 4517-4523

DOI https://doi.org/10.1248/cpb.35.4517

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Abstract

An efficient method for the synthesis of monosaccharide analogs of the nonreducing sugar moiety of lipid A is described. A brief analysis of their biological activities is also presented.

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