1987 年 35 巻 12 号 p. 5028-5031
Platinum pyrimidine greens are very effective against L1210 cells, but the blues are inactive. A clear relationship between the activity and size of Pt-green molecules has been observed; smaller molecules with up to Pt-decanuclear complexes are much more active than larger ones. Formation of macrocells by the greens have been found for the first time with L1210 cells. The more active the green complex is, the denser is the population of the macrocells. These findings could be related to the membrane permeability.