Synthesis and Thermal Cyclization Reactions of Methyl Isocrotonate Derivatives

NORIO KAWAHARA; TAKAKO SHIMAMORI; TSUNEO ITOH; HIROAKI TAKAYANAGI; HARUO OGURA

doi:10.1248/cpb.35.457

NORIO KAWAHARA, TAKAKO SHIMAMORI, TSUNEO ITOH, HIROAKI TAKAYANAGI, HARUO OGURA

著者情報

キーワード: cyclization, thermal reaction, methyl isocrotonate derivative, X-ray analysis, pyrido [1, 2-a] pyrazine, pyrido [1, 2-a] quinoxaline, pyrido [2, 1-c] -1, 4-oxazine, pyrido [2, 1-c] -1, 4-benzoxazine, dimethyl acetylenedicarboxylate

ジャーナルフリー

1987 年 35 巻 2 号 p. 457-467

DOI https://doi.org/10.1248/cpb.35.457

詳細

抄録

Methyl isocrotonate derivatives prepared from various 1, 2-ethylenediamines, ο-phenylenediamines, 2-aminoethanols or ο-aminophenols with dimethyl acetylenedicarboxylate were easily converted to pyrido [1, 2-a] pyrazines, pyrido [1, 2-a] quinoxalines, pyrido [2, 1-c] -1, 4-oxazines, pyrido- [2, 1-c] -1, 4-benzoxazines, respectively, and other cyclization compounds by means of thermal reactions.

責任著者(Corresponding author)

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