NMR EVIDENCE FOR THE UNEXPECTED INTERCONVERSION OF 2-DEOXY-2-FLUORO-D-GLUCOSE AND 2-DEOXY-2-FLUORO-D-MANNOSE IN MICE

Yoko Kanazawa; Yuko Momozono; Hideki Yamane; Terushi Haradahira; Minoru Maeda; Masaharu Kojimaa

doi:10.1248/cpb.35.895

Yoko Kanazawa, Yuko Momozono, Hideki Yamane, Terushi Haradahira, Minoru Maeda, Masaharu Kojimaa

著者情報

キーワード: 2-deoxy-2-fluoro-D-glucose, 2-deoxy-2-fluoro-D-mannose, epimerization, in vivo NMR, ¹⁹F NMR

ジャーナルフリー

1987 年 35 巻 2 号 p. 895-897

DOI https://doi.org/10.1248/cpb.35.895

詳細

抄録

2-Deoxy-2-fluoro-D-glucose (FDG) or its 6-phosphate (FDG-6-P) was detected by¹⁹F NMR in the organs and urine of mice previously injected with 2-deoxy-2-fluoro-D-mannose (FDM). This conversion of FDG (-6-P) to FDM (-6-P) in vivo was reversible.

責任著者(Corresponding author)

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