Abstract
The chronic effect of oral administration of Salviae Miltiorrhizae Radix extract on renal tissue blood flow and blood pressure was investigated in uremic rats. Chronic administration of the aqueous extract from Salviae Miltiorrhizae Radix to rats significantly increased renal tissue blood flow by 32 and 38% on days 12 and 24, respectively. Blood pressure measured by the tail-cuff method was significantly decreased by 4-8% on the 6th, 18th, and 24th d. The uremia-alleviating action of Salviae Miltiorrhizae Radix extract is discussed on the basis of the present results.
