Antitumor Principles from Ginkgo biloba L.

HIDER ITOKAWA; NOBUO TOTSUKA; KEISUKE NAKAHARA; KOICHI TAKEYA; JEAN-PIERRE LEPOITTEVIN; YOSHINORI ASAKAWA

doi:10.1248/cpb.35.3016

Antitumor Principles from Ginkgo biloba L.

HIDER ITOKAWA, NOBUO TOTSUKA, KEISUKE NAKAHARA, KOICHI TAKEYA, JEAN-PIERRE LEPOITTEVIN, YOSHINORI ASAKAWA

著者情報

キーワード: Ginkgo biloba, Ginkgoaceae, antitumor activity, Sarcoma 180 ascites, anacardic acid, bilobol, cardanol

ジャーナルフリー

1987 年 35 巻 7 号 p. 3016-3020

DOI https://doi.org/10.1248/cpb.35.3016

詳細

抄録

Seven long-chain phenols were isolated from Ginkgo biloba L. Three of them, anacardic acid (Ib), bilobol (IIa), and cardanol (IIIa), showed antitumor activity against Sarcoma 180 ascites in mice. The antitumor effectiveness was rated (+ +) for Ib, (+ + +) for IIa, and (+ + +) for IIIa at 40 mg/kg/d by the total packed cell volume method.

責任著者(Corresponding author)

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