SELECTIVE SYNTHESIS OF NOVEL ANTICANCER PLATINUM PYRIMIDINE GREENS BY HYDROGEN PEROXIDE OXIDATION
キーワード:
antitumor activity
1988 年 36 巻 1 号 p. 448-451
詳細
1988 年 36 巻 1 号 p. 448-451
Platinum greens can be synthesized effectively and selectively from aquated cis-diiododiammineplatinum(II) and pyrimidine derivatives with hydrogen peroxide under argon. By adjusting reaction temperature, time and the amount of oxidizing agent, various sizes of the molecule have been obtained. This method can be used with the different substrates and counter anions of the complexes.
