New Constituents of the Aril of Myristica fragrans

Abstract

The following constituents were isolated for the first time from the aril of Myristica fragrans HOUTT. : 3-(3, 4, 5-trimethoxyphenyl)-2-(E)-propen-1-ol (1), 3-(3-methoxy-4, 5-methylenedioxyphenyl)-2-(E)-propen-1-ol (2), 2, 3-dihydro-7-methoxy-2-(3, 4-dimethoxyphenyl)-3-methyl-5-(1-(E)-propenyl)benzofuran (3), fragransol-C (4), fragransol-D (5), 2, 3-dimethyl-1, 4-bis-(3, 4-methylenedioxyphenyl)butan-1-ol (6), myristicanol-A (7) and myristicanol-B (8). Compounds 4, 5, 7 and 8 are new neolignans which may be formed by coupling of cinnamyl alcohol and propenylbenzene unis.