Abstract
Hexestrol showed antifungal activity on plant-pathogenic fungi phytogrowth-inhibitory activity and a hypotensive effect on rats. Firstly, hexestrol exhibited antifungal activity on all plantpathogenic fungi tested except for Rhizoctonia solani IFO-30464 and Ceratoystis fimbriata IFO-4864. In particular, hexestrol strongly inhibited the growth of Fusarium oxsporum f. sp. lycopersici IFO-6531 (minimal inhibitory concentration : 5 μg/ml). Secondly, hexestrol had inhibitory activity on the growth of the root of Raphanus sativus L. var. raphanistroides MAKINO even at the low concentrarion of 50 ppm. Thirdly, hexestrol showed a transient hypotensive effect on rats (-40.00±2.60 mmHg, 10 mg/kg, i.v.).
