Condensed Heteroaromatic Ring Systems. XIII. : One-Step Synthesis of 2-Substituted 1-Methylsulfonylindoles from N-(2-Halophenyl)methanesulfonamides
1988 年 36 巻 4 号 p. 1305-1308
詳細
1988 年 36 巻 4 号 p. 1305-1308
The reaction of N-(2-bromophenyl)-and N-(2-iodophenyl)methanesulfonamide with terminal acetylenes in the presence of dichlorobis(triphenylphosphine)palladium yielded 1-methylsulfonyl-indoles having carbon-functional groups at the 2-position, such as hydroxmethyl, 2-hydroxyethyl, diethoxymethyl, 2-ethoxycarbonylethyl, etc., in one step.
