Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Palladium-Catalyzed Coupling Reaction of 3-Iodoindoles and 3-Iodobenzo[b]thiophene with Terminal Acetylenes
坂本 尚夫永野 辰夫根東 義則山中 宏
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キーワード: 3-ethynylbenzo[b]thiophene
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1988 年 36 巻 6 号 p. 2248-2252

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The palladium-catalyzed coupling reaction of 3-iodoindoles possessing an electron-withdrawing group at the 1- or 2-position with terminal acetylenes smoothly proceeded to yield 3-ethynylindoles. Similarly, the reaction of 3-iodobenzo[b]thiophene gave the expected products, but the reaction of 3-bromobenzo[b]furan provided resinous materials.

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© The Pharmaceutical Society of Japan
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