Amides from Huajiao, Pericarps of Zanthoxylum bungeanum MAXIM.

Abstract

From Huajiao, the pericarps of Zanthoxylum bungeanum MAXIM. (Rutaceae), six unsaturated aliphatic acid amides (1-6) were isolated. Of these, three were identical with the known amides, hydroxy-α-, hydroxy-β- and hydroxy-γ-sanshools(1, 2 and 3). The other three are new compounds, and the structures were established as (2E, 4E, 8E, 10E, 12E)-2'-hydroxy-N-isobutyl-2, 4, 8, 10, 12-tetradecapentaenamide, and (2E, 4E, 8Z, 11Z)- and (2E, 4E, 8Z, 11E)-2'-hydroxy-N-isobutyl-2, 4, 8, 11-tetradecatetraenamide (4, 5 and 6, respectively).