Regioselective Introduction of a Methoxy Group at the Benzylic Position of Isochromane Derivatives by Cerium(IV) Oxidation in Methanol

Kimiaki ISOBE; Naoko TAKEDA; Kunihiko MOHRI; Yoshisuke TSUDA

doi:10.1248/cpb.37.3390

磯部公明, 武田尚子, 毛利邦彦, 津田喜典

著者情報

キーワード: ceric ammonium nitrate (CAN), methanol, regioselective methoxylation, isochromane, methoxyisochroman-3-one, benzylic oxidation, methoxylation

ジャーナルフリー

1989 年 37 巻 12 号 p. 3390-3392

DOI https://doi.org/10.1248/cpb.37.3390

詳細

抄録

The oxidation of methoxy-isochromans and -isochromanones with ceric ammonium nitrate in methanol introduced a new methoxy group regioselectively at a benzylic position para to the methoxy function on the aromatic nucleus.

責任著者(Corresponding author)

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